Public/Remove-WPFComboBoxItem.ps1

function Remove-WPFComboBoxItem
{
<#
    .SYNOPSIS
        Function to Remove items from a ComboBox
     
    .DESCRIPTION
        Function to Remove items from a ComboBox
     
        System.windows.controls.combobox
        https://msdn.microsoft.com/en-us/library/system.windows.controls.combobox(v=vs.110).aspx
     
    .PARAMETER ComboBox
        Specifies the ComboBox control
     
    .PARAMETER SelectedItem
        Specifies the Selected item(s)
     
    .EXAMPLE
        Remove-WPFComboBoxItem -ComboBox $Combobox1 -SelectedItem
     
        Will remove all the selected item in the ComboBox $Combobox1
         
    .NOTES
        Francois-Xavier Cat
        lazywinadmin.com
        @lazywinadm
        github.com/lazywinadmin
#>

    Param (
        [ValidateNotNull()]
        [Parameter(Mandatory = $true)]
        [System.Windows.Controls.ComboBox]$ComboBox,
        
        [switch]$SelectedItem
    )
    BEGIN
    {
        Add-Type –assemblyName PresentationFramework
        Add-Type –assemblyName PresentationCore
        Add-Type –assemblyName WindowsBase
    }
    PROCESS
    {
        IF ($PSBoundParameters['SelectedItem'])
        {
            Foreach ($item in $ComboBox.SelectedItem)
            {
                $ComboBox.Items.RemoveAt($comboBox.SelectedIndex)
                #$ComboBox.Items.Remove($comboBox.SelectedItem)
            }
        }
    }
}